Deficiencies inside us bring about a spiritual void or the lack of wholeness (fullness). As we lay the foundation of our lives on deficiencies or weaknesses, the result is suffering, sorrow and peacelessness. If we act in harmony with spiritual virtues and qualities, the result is cooperation, happiness, peace, contentment and finally, wholeness.
A spiritual void leads to selfishness and causes the creation of greed inside us. We want to have more and possess more, which generates a state of expectation and stress. We fill our lives with things and objects to cover up deeper deficiencies. Then we are afraid of losing them. We generate expectations of all kinds, and when they are not fulfilled we react with anger, frustration, fear or disappointment. The inner emptiness makes us become greedy. We fill ourselves with objects, properties, things. We take and consume more than what we can give to the Universe in the form of positive thoughts, feelings, vibrations, actions etc. and this brings about imbalances in the self, in relation to others and with nature.
Something similar happens on a physical level. The body has a capacity to recycle and eliminate waste through different mediums. However, since we consume more toxins than the body can process, it leads to imbalance and we are more prone to feeling physically ill and unfit and developing diseases etc.